Profile: Prof. Stephen Clarke

Issue: Vol.7, No.3 - July 2008

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Article Type: Profile

Prof. Stephen Clarke

Prof. Stephen Clarke, a world renowned expert in the field of Cancer Pharmacology and Oncology, is presently working as Professor of Medicine in the Sydney Cancer Centre, one of Australia's leading cancer centres.

Prof. Stephen Clarke is a medical oncologist and translational cancer researcher based at the University of Sydney in NSW, Australia. Prof. Clarke obtained his medical degree (MB BS) through the University of Sydney in 1983. He completed an FRACP in Medical Oncology in 1990. From 1991-1994, Prof. Clarke worked in the Drug Development Unit of the Institute of Cancer Research/Royal Marsden Cancer Hospital in Sutton, Surrey, UK. He obtained a PhD in cancer pharmacology from the University of London. He returned to Australia in 1994. His clinical practice is at the Sydney Cancer Centre, where he has a major interest in colorectal cancer. Prof. Clarke is also Head of the Cancer Pharmacology Unit at the Sydney Cancer Centre, where he has undertaken extensive research on predictors of toxicity for a range of cytotoxic drugs including raltitrexed, pemetrexed, irinotecan, docetaxel and capecitabine. He is also involved in the assessment of proteomic predictors of outcome in patients with colorectal cancer. In addition, his laboratory has made major findings in relation to the impact of cancer associated inflammation on chemotherapy toxicity and survival. He has been an invited speaker at numerous national and international meetings and has over 100 publications in peer-reviewed journals. Prof. Clarke has been a reviewer for many journals and is on the editorial boards of Australian Prescriber and the Asia Pacific Journal of Oncology. He is the Oncology Adviser for the Australian Department of Veterans' Affairs, and is a member of the Australian Drug Evaluation Committee (ADEC) and the Repatriation Pharmaceutical Reference Committee.

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