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TRPM8, A Calcium Permeable Non-selective Cation Channel

Issue: Vol.10, No.4 - October 2011

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Article Type: Manuscript

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  1. Dr Zhong-Ping Feng
    Department of Physiology, University of Toronto, , rn

TRPM8 is known as a cold-sensing channel, which is permeable to calcium and monovalent cations. It was originally identified in prostate cancer cells. The physiological and pathological functions of TRPM8 in prostate cells remain unclear, however, it has been suggested the channel may serve as a diagnostic and prognostic marker in prostate cancer. This mini-review highlights our current understanding of TRPM8.

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