Print

Profile of Pediatric Cancer Patients Treated with External Beam Radiation Therapy Under Anesthesia at a Regional Cancer Center of India

Issue: Vol.8, No.4 - October 2009

« Back to Articles

Article Type: Manuscript

Download PDF Version »

  1. Dr Dayanand Sharma
    Department of Radiation Oncology, All India Institute of Medical Sciences
  2. Goura Kishor Rath
  3. Monica Malik
  4. Sushma Bhatnagar
  5. Amit Bahl
  6. Parmod Kumar Julka

Aim: To study the clinical profile of children treated by external beam radiation therapy (EBRT) under anesthesia at our center.
Material and Methods: Clinical case records of all the pediatric patients who underwent EBRT under anesthesia were retrieved. From each case file, data regarding the patient's demographic details, diagnosis, EBRT details, site of irradiation, events occurring during the course of EBRT, etc. were recorded.
Results: During the 2 years period (June 2002 to June 2004), 130 case records were retrieved. A total of 1793 treatment fractions were administered in 130 patients (average 13.8 fractions per patient) with some kind of anesthesia or behavioral therapy (BT). Age ranged from 1-13 years (median age 5 year). Common malignancies included acute lymphocytic leukemia (ALL), retinoblastoma (RB), Wilm's tumor (WT), lymphomas and rhabdomyosarcoma (RMS). Seven patients received palliative radiation therapy (RT) and 123 received curative/adjuvant RT. Common sites of irradiation were cranium, head and neck, orbit and abdomen. The intended duration of treatment course ranged from 1-42 days. Twenty two patients required treatment interruption due to treatment related toxicity. Median duration of treatment interruption was 6 days.
Conclusion: About 2% of all EBRT treatments are carried out under anesthesia at our centre. Good BT reduces the need of anesthesia. Such measures should be fully explored in countries with limited setup for EBRT under anesthesia. But, the increasing use of modern RT techniques like IMRT, 3D-CRT where strict immobilization is the key aspect, may increase the need of anesthesia in pediatric RT.

Download PDF Version »

Favourites   Share / Bookmark

Also In This Issue

« Back to Articles