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New Approaches for Early Detection of Ulcerative Colitis (UC) Associated Cancer and Surgical Treatment of UC Patients

Issue: Vol.10, No.4 - October 2011

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Article Type: Manuscript

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  1. Dr Toshiaki Watanabe
    Department of Surgeryrn
    Teikyo University School of Medicine,

The number of ulcerative colitis (UC) patients in Japan has been increasing. Previous studies show colonoscopic surveillance to be useful for the early detection of UCassociated colorectal cancers. Recently, studies show that chromoendoscopy is useful for performing a targeted biopsy instead of a step biopsy to improve the efficacy of surveillance. Another approach to improve the efficacy of surveillance is to identify molecular markers for high-risk patients. A microarray analysis might be useful for the selection of highrisk patients. A prospective randomized controlled study is presently being conducted in Japan to compare the efficacy of a step biopsy and a target biopsy.

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