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Assessment of Prognostic Factors for Non-Small-Cell Lung Carcinoma Following Radiotherapy of Cerebral Metastases

Issue: Vol.7, No.3 - July 2008

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Article Type: Manuscript

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  1. Maria Mazurkiewicz
  2. A Brzozowska
  3. T Mazurkiewicz

The study involved 50 patients with non-small-cell lung cancer presenting brain metastases. For 24 patients brain metastasis was the initial complaint. All patients had undergone cranial irradiation with a volume of 2000 cGy /g (5 x 400 cGy/g). We assessed a significance of selected prognostic factors (age, sex, number of brain metastases, histopathologic type, time interval between the diagnosis of lung cancer to the occurrence of brain metastasis) for the survival time. The median survival time calculated from the completion of radiotherapy of brain metastasis was 4,42 months. There was no statistically significant correlation between the median survival time and the analysed prognostic factors. Accordingly, further research of some other prognostic factors seems reasonable that would allow to identify patients likely to profit from NSCLC radiotherapy of brain metastasis as far as the survival duration .

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